합성 저분자 API 시장 규모, 점유율, 동향 분석 보고서 : 제조업체별, 용도별, 지역별, 부문별 예측(2025-2030년)

Synthetic Small Molecule API Market Growth & Trends:

The global synthetic small molecule API market size is estimated to reach USD 257.4 billion by 2030, registering a CAGR of 5.6% from 2025 to 2030, according to a new report by Grand View Research, Inc. This can be attributed to the increasing demand for pharmaceuticals and new small molecule-based drugs globally. Moreover, small molecules API offers versatility between dosage forms and has an easier means of purification, which makes it more acceptable and increases the demand.

There is an increasing dominance of synthetic drugs in the pharmaceutical industry, which is expected to propel the requirement of raw materials such as small molecule APIs for production. Moreover, technological advancements related to the enhancement of existing products are expected to provide new opportunities for small molecule therapeutics. For instance, in March 2022, Evonik launched the new EUDRATECSoluFlow technology that enhances the solubility of oral small molecules.

The market is driven by positive government support for the production of APIs in various regions, particularly in Asia, where the majority of API manufacturers are dependent on the supply of API for the production of synthetic small molecule APIs. There has been an increasing focus on outsourcing activities for API production. For instance, in April 2020, for managing COVID-19, Wavelength Pharmaceuticals expanded the supply of key drug ingredients for certain pharmaceutical products needed to manage respiratory critical care patients and launched API CDMO services. Emerging markets such as China, India, and Southeast Asia represent significant opportunities for growth.

The investment in new and complex technologies is relatively low for Asian manufacturers as they are more focused on less complex molecules that can be produced in bulk. Thus, the investment in high-yielding, low-cost technologies is an alternative for manufacturers in other developed regions such as Europe and North America to avoid competitive pressure.

Key players operating in the market are focusing on collaboration for the production of potent API products. For instance, in August 2021, Almac Sciences signed an agreement with Pila Pharma for the production of the API XEN-D0501, a highly potent and selective small molecule TRPV1 antagonist. Moreover, CDMOs are constantly evolving by expanding their capacities to meet the heightened demand for synthetic drugs. For instance, in April 2022, AGC Inc. announced the expansion of its Spanish facility by 7500 m2 for synthetic pharmaceutical production, which is expected to enhance the demand for synthetic small molecule active pharmaceutical ingredients in the region.

Synthetic Small Molecule API Market Report Highlights:

• The growth of the overall market is attributed to the increasing production of pharmaceuticals with the increased demand for raw material
• The API market is witnessing a key shift with the rise in the preference for CDMOs for the production of synthetic small molecule active pharmaceutical ingredients in bulk
• By manufacturer, the outsourced segment is expected to witness fastest CAGR over the forecast period, owing to a dependency of small and mid-sized companies on outsourcing for commercial production
• By application, the cardiovascular diseases segment dominated the market in 2024 with a market share of 21.7%, owing to their chronic nature and high global prevalence.
• North America dominated the market in 2024, due to the presence of key players and rising support from the government for enhancing the API manufacturing capacity of the region.

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Market Segmentation & Scope
• 1.2. Segment Definitions
  • 1.2.1. Manufacturer
  • 1.2.2. Application
• 1.3. Estimates and Forecast Timeline
• 1.4. Research Methodology
• 1.5. Information Procurement
  • 1.5.1. Purchased Database
  • 1.5.2. GVR's Internal Database
  • 1.5.3. Secondary Sources
  • 1.5.4. Primary Research
• 1.6. Information Analysis
  • 1.6.1. Data Analysis Models
• 1.7. Market Formulation & Data Visualization
• 1.8. Model Details
  • 1.8.1. Commodity Flow Analysis
• 1.9. List of Secondary Sources
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Snapshot
• 2.2. Segment Snapshot
• 2.3. Competitive Landscape Snapshot

Chapter 3. Synthetic Small Molecule API Market Variables, Trends, & Scope

• 3.1. Market Lineage Outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
  • 3.2.2. Market Restraint Analysis
• 3.3. Business Environment Analysis
  • 3.3.1. Industry Analysis - Porter's Five Forces Analysis
    • 3.3.1.1. Supplier Power
    • 3.3.1.2. Buyer Power
    • 3.3.1.3. Substitution Threat
    • 3.3.1.4. Threat of New Entrants
    • 3.3.1.5. Competitive Rivalry
  • 3.3.2. PESTLE Analysis

Chapter 4. Synthetic Small Molecule API Market: Manufacturer Business Analysis

• 4.1. Manufacturer Market Share, 2024 & 2030
• 4.2. Manufacturer Segment Dashboard
• 4.3. Market Size & Forecasts and Trend Analysis, by Manufacturer, 2018 to 2030 (USD Billion)
• 4.4. In-house
  • 4.4.1. In-house Market, 2018 - 2030 (USD Billion)
• 4.5. Outsourced
  • 4.5.1. Outsourced Market, 2018 - 2030 (USD Billion)

Chapter 5. Synthetic Small Molecule API Market: Application Business Analysis

• 5.1. Application Market Share, 2024 & 2030
• 5.2. Application Segment Dashboard
• 5.3. Market Size & Forecasts and Trend Analysis, by Application, 2018 to 2030 (USD Billion)
• 5.4. Cardiovascular Diseases
  • 5.4.1. Cardiovascular Diseases Market, 2018 - 2030 (USD Billion)
• 5.5. Oncology
  • 5.5.1. Oncology Market, 2018 - 2030 (USD Billion)
• 5.6. CNS and Neurology
  • 5.6.1. CNS and Neurology Market, 2018 - 2030 (USD Billion)
• 5.7. Orthopedic
  • 5.7.1. Orthopedic Market, 2018 - 2030 (USD Billion)
• 5.8. Outsourced
  • 5.8.1. Outsourced Market, 2018 - 2030 (USD Billion)
• 5.9. Endocrinology
  • 5.9.1. Endocrinology Market, 2018 - 2030 (USD Billion)
• 5.10. Pulmonology
  • 5.10.1. Pulmonology Market, 2018 - 2030 (USD Billion)
• 5.11. Gastroenterology
  • 5.11.1. Gastroenterology Market, 2018 - 2030 (USD Billion)
• 5.12. Nephrology
  • 5.12.1. Nephrology Market, 2018 - 2030 (USD Billion)
• 5.13. Ophthalmology
  • 5.13.1. Ophthalmology Market, 2018 - 2030 (USD Billion)
• 5.14. Others
  • 5.14.1. Others Market, 2018 - 2030 (USD Billion)

Chapter 6. Synthetic Small Molecule API Market: Regional Estimates & Trend Analysis Manufacturer and Application

• 6.1. Regional Market Share Analysis, 2024 & 2030
• 6.2. Regional Market Dashboard
• 6.3. Market Size & Forecasts Trend Analysis, 2018 to 2030:
• 6.4. North America
  • 6.4.1. North America Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.4.2. U.S.
    • 6.4.2.1. Key Country Dynamics
    • 6.4.2.2. Regulatory Framework
    • 6.4.2.3. Competitive Insights
    • 6.4.2.4. U.S. Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.4.3. Canada
    • 6.4.3.1. Key Country Dynamics
    • 6.4.3.2. Regulatory Framework
    • 6.4.3.3. Competitive Insights
    • 6.4.3.4. Canada Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.4.4. Mexico
    • 6.4.4.1. Key Country Dynamics
    • 6.4.4.2. Regulatory Framework
    • 6.4.4.3. Competitive Insights
    • 6.4.4.4. Mexico Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
• 6.5. Europe
  • 6.5.1. Europe Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.2. UK
    • 6.5.2.1. Key Country Dynamics
    • 6.5.2.2. Regulatory Framework
    • 6.5.2.3. Competitive Insights
    • 6.5.2.4. UK Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.3. Germany
    • 6.5.3.1. Key Country Dynamics
    • 6.5.3.2. Regulatory Framework
    • 6.5.3.3. Competitive Insights
    • 6.5.3.4. Germany Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.4. France
    • 6.5.4.1. Key Country Dynamics
    • 6.5.4.2. Regulatory Framework
    • 6.5.4.3. Competitive Insights
    • 6.5.4.4. France Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.5. Italy
    • 6.5.5.1. Key Country Dynamics
    • 6.5.5.2. Regulatory Framework
    • 6.5.5.3. Competitive Insights
    • 6.5.5.4. Italy Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.6. Spain
    • 6.5.6.1. Key Country Dynamics
    • 6.5.6.2. Regulatory Framework
    • 6.5.6.3. Competitive Insights
    • 6.5.6.4. Spain Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.7. Denmark
    • 6.5.7.1. Key Country Dynamics
    • 6.5.7.2. Regulatory Framework
    • 6.5.7.3. Competitive Insights
    • 6.5.7.4. Denmark Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.5.8. Sweden
    • 6.5.8.1. Key Country Dynamics
    • 6.5.8.2. Regulatory Framework
    • 6.5.8.3. Competitive Insights
    • 6.5.8.4. Sweden Synthetic Small Molecule API Market Estimates And Forecasts, By Country, 2018 - 2030 (USD Billion)
  • 6.5.9. Norway
    • 6.5.9.1. Key Country Dynamics
    • 6.5.9.2. Regulatory Framework
    • 6.5.9.3. Competitive Insights
    • 6.5.9.4. Norway Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
• 6.6. Asia Pacific
  • 6.6.1. Asia Pacific Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.6.2. Japan
    • 6.6.2.1. Key Country Dynamics
    • 6.6.2.2. Regulatory Framework
    • 6.6.2.3. Competitive Insights
    • 6.6.2.4. Japan Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.6.3. China
    • 6.6.3.1. Key Country Dynamics
    • 6.6.3.2. Regulatory Framework
    • 6.6.3.3. Competitive Insights
    • 6.6.3.4. China Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.6.4. India
    • 6.6.4.1. Key Country Dynamics
    • 6.6.4.2. Regulatory Framework
    • 6.6.4.3. Competitive Insights
    • 6.6.4.4. India Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.6.5. Australia
    • 6.6.5.1. Key Country Dynamics
    • 6.6.5.2. Regulatory Framework
    • 6.6.5.3. Competitive Insights
    • 6.6.5.4. Australia Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.6.6. South Korea
    • 6.6.6.1. Key Country Dynamics
    • 6.6.6.2. Regulatory Framework
    • 6.6.6.3. Competitive Insights
    • 6.6.6.4. South Korea Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.6.7. Thailand
    • 6.6.7.1. Key Country Dynamics
    • 6.6.7.2. Regulatory Framework
    • 6.6.7.3. Competitive Insights
    • 6.6.7.4. Thailand Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
• 6.7. Latin America
  • 6.7.1. Latin America Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.7.2. Brazil
    • 6.7.2.1. Key Country Dynamics
    • 6.7.2.2. Regulatory Framework
    • 6.7.2.3. Competitive Insights
    • 6.7.2.4. Brazil Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.7.3. Argentina
    • 6.7.3.1. Key Country Dynamics
    • 6.7.3.2. Regulatory Framework
    • 6.7.3.3. Competitive Insights
    • 6.7.3.4. Argentina Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
• 6.8. MEA
  • 6.8.1. MEA Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.8.2. South Africa
    • 6.8.2.1. Key Country Dynamics
    • 6.8.2.2. Regulatory Framework
    • 6.8.2.3. Competitive Insights
    • 6.8.2.4. South Africa Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.8.3. Saudi Arabia
    • 6.8.3.1. Key Country Dynamics
    • 6.8.3.2. Regulatory Framework
    • 6.8.3.3. Competitive Insights
    • 6.8.3.4. Saudi Arabia Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.8.4. UAE
    • 6.8.4.1. Key Country Dynamics
    • 6.8.4.2. Regulatory Framework
    • 6.8.4.3. Competitive Insights
    • 6.8.4.4. UAE Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)
  • 6.8.5. Kuwait
    • 6.8.5.1. Key Country Dynamics
    • 6.8.5.2. Regulatory Framework
    • 6.8.5.3. Competitive Insights
    • 6.8.5.4. Kuwait Synthetic Small Molecule API Market Estimates And Forecasts, 2018 - 2030 (USD Billion)

Chapter 7. Competitive Landscape

• 7.1. Participant Overview
• 7.2. Company Market Position Analysis
• 7.3. Company Categorization
• 7.4. Strategy Mapping
• 7.5. Company Profiles/Listing
  • 7.5.1. Merck & Co., Inc.
    • 7.5.1.1. Overview
    • 7.5.1.2. Financial Performance
    • 7.5.1.3. Product Benchmarking
    • 7.5.1.4. Strategic Initiatives
  • 7.5.2. AbbVie, Inc.
    • 7.5.2.1. Overview
    • 7.5.2.2. Financial Performance
    • 7.5.2.3. Product Benchmarking
    • 7.5.2.4. Strategic Initiatives
  • 7.5.3. Bristol-Myers Squibb Company
    • 7.5.3.1. Overview
    • 7.5.3.2. Financial Performance
    • 7.5.3.3. Product Benchmarking
    • 7.5.3.4. Strategic Initiatives
  • 7.5.4. Albemarle Corporation
    • 7.5.4.1. Overview
    • 7.5.4.2. Financial Performance
    • 7.5.4.3. Product Benchmarking
    • 7.5.4.4. Strategic Initiatives
  • 7.5.5. Boehringer Ingelheim International GmbH
    • 7.5.5.1. Overview
    • 7.5.5.2. Financial Performance
    • 7.5.5.3. Product Benchmarking
    • 7.5.5.4. Strategic Initiatives
  • 7.5.6. Cipla, Inc.
    • 7.5.6.1. Overview
    • 7.5.6.2. Financial Performance
    • 7.5.6.3. Product Benchmarking
    • 7.5.6.4. Strategic Initiatives
  • 7.5.7. Dr. Reddy's Laboratories Ltd.
    • 7.5.7.1. Overview
    • 7.5.7.2. Financial Performance
    • 7.5.7.3. Product Benchmarking
    • 7.5.7.4. Strategic Initiatives
  • 7.5.8. Aurobindo Pharma
    • 7.5.8.1. Overview
    • 7.5.8.2. Financial Performance
    • 7.5.8.3. Product Benchmarking
    • 7.5.8.4. Strategic Initiatives
  • 7.5.9. Sun Pharmaceutical Industries Ltd.
    • 7.5.9.1. Overview
    • 7.5.9.2. Financial Performance
    • 7.5.9.3. Product Benchmarking
    • 7.5.9.4. Strategic Initiatives