전장 유전체 바이설파이트 시퀀싱 시장 - 규모, 점유율, 동향 분석 보고서 : 제품 및 서비스별, 워크플로우별, 용도별, 최종 용도별, 지역별 부문 예측(2025-2030년)

Whole Genome Bisulfite Sequencing Market Growth & Trends:

The global whole genome bisulfite sequencing market size is anticipated to reach USD 749.4 million by 2030 and is expected to grow at a CAGR of 16.8% from 2025 to 2030, according to a new report by Grand View Research, Inc. The market is experiencing substantial growth, driven by increasing research in epigenetics and DNA methylation studies. Epigenetic modifications, particularly DNA methylation, play a critical role in gene regulation, cancer progression, neurological disorders, and developmental biology. The demand for advanced sequencing technologies to decode these modifications is propelling the adoption of whole genome bisulfite sequencing. As scientists strive to understand the link between methylation patterns and disease states, whole genome bisulfite sequencing has emerged as the gold standard for genome-wide methylation analysis, offering single-nucleotide resolution. This has led to its growing application in biomarker discovery, precision medicine, and drug development.

The rise in funding from both government agencies and private investors has significantly contributed to the expansion of whole genome bisulfite sequencing technologies. Numerous national and international research initiatives are being launched to investigate epigenetic markers associated with various diseases, further fueling market growth. Pharmaceutical and biotechnology companies are investing heavily in sequencing technologies, leveraging whole genome bisulfite sequencing to develop targeted therapies and personalized treatment plans. With the growing emphasis on precision medicine, whole genome bisulfite sequencing is becoming an essential tool for understanding genetic and epigenetic variations among individuals, allowing for more effective drug development and disease management.

Technological advancements have also played a crucial role in the expansion of the whole genome bisulfite sequencing market. The development of high-throughput sequencing platforms, improved bisulfite conversion methods, and enzyme-based alternatives have enhanced data accuracy, efficiency, and overall sequencing output. The introduction of more cost-effective and streamlined workflows has made whole genome bisulfite sequencing more accessible to researchers, reducing the financial barriers that previously limited its adoption. Companies are constantly innovating to create faster, more reliable sequencing solutions, minimizing DNA damage and bias associated with traditional bisulfite conversion methods. The increasing availability of automation and cloud-based bioinformatics solutions has further facilitated the widespread adoption of whole genome bisulfite sequencing, enabling researchers to process large datasets with greater efficiency and accuracy.

The growing applications of whole genome bisulfite sequencing across various research fields, including oncology, stem cell research, neuroscience, and developmental biology, have also contributed to its market expansion. Cancer research, in particular, has been a significant driver, as methylation changes are widely recognized as key indicators of tumorigenesis. By mapping methylation patterns across the genome, researchers can identify potential biomarkers for early cancer detection, prognosis, and therapeutic targeting. Similarly, whole genome bisulfite sequencing is being extensively used in stem cell research to study cellular differentiation and reprogramming, offering valuable insights into regenerative medicine. The technique is also gaining traction in neuroscience, where it is used to explore epigenetic changes associated with neurodegenerative disorders such as Alzheimer's and Parkinson's disease.

Despite the strong growth trajectory, the whole genome bisulfite sequencing market faces several challenges that may hinder its expansion. One of the primary restraints is the high cost associated with whole genome bisulfite sequencing. The complex workflow, expensive reagents, and requirement for high-performance computing infrastructure contribute to the overall cost burden, making it less accessible to smaller research laboratories and institutions with limited budgets.

Whole Genome Bisulfite Sequencing Market Report Highlights:

• Based on product & service, kits & reagents segment dominated the market in 2024 with a share of 59.9% due to the high demand for sequencing consumables, recurring purchases, and widespread adoption in research.
• The sequencing workflow segment dominated the market in 2024 as it plays an essential role in sample processing, data generation, and widespread adoption in research and diagnostics.
• Based on application, the drug development segment dominated in 2024 due to the extensive use of whole genome bisulfite sequencing in biomarker discovery, epigenetic profiling, and precision medicine advancements.
• Based on end use, the academic & research institutes segment dominated the end-use market with a share of 51.1% in 2024. The extensive involvement of these institutions in epigenetics, disease mechanism studies, and genome-wide methylation analysis, is driving the segment growth.
• North America region dominated the whole genome bisulfite sequencing market with a share of 48.9% in 2024, owing to factors such as high penetration of research and development activities in the region.

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Market Segmentation and Scope
• 1.2. Market Definitions
  • 1.2.1. Product & Service
  • 1.2.2. Workflow
  • 1.2.3. Application
  • 1.2.4. End Use
• 1.3. Information analysis
• 1.4. Market formulation & data visualization
• 1.5. Data validation & publishing
• 1.6. Information Procurement
  • 1.6.1. Primary Research
• 1.7. Information or Data Analysis
• 1.8. Market Formulation & Validation
• 1.9. Market Model
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Outlook
• 2.2. Segment Snapshot
• 2.3. Competitive Insights

Chapter 3. Whole Genome Bisulfite Sequencing Market Variables, Trends, & Scope

• 3.1. Market Lineage Outlook
  • 3.1.1. Parent Market Outlook
  • 3.1.2. Related/Ancillary Market Outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
    • 3.2.1.1. Decreasing Costs of Sequencing Techniques
    • 3.2.1.2. Advancements in Bisulfite Conversion Techniques
    • 3.2.1.3. Growing Demand for Precision Medicine
  • 3.2.2. Market Restraint Analysis
    • 3.2.2.1. Complex Data Analysis & Interpretation
    • 3.2.2.2. High Computational & Storage Requirements
• 3.3. Industry Analysis Tools
  • 3.3.1. Porter's Five Forces Analysis
  • 3.3.2. PESTEL Analysis
  • 3.3.3. COVID-19 Impact Analysis

Chapter 4. Whole Genome Bisulfite Sequencing Market: Product & Service Estimates & Trend Analysis

• 4.1. Product & Service Segment Dashboard
• 4.2. Global Whole Genome Bisulfite Sequencing Market Product & Service Movement Analysis
• 4.3. Global Whole Genome Bisulfite Sequencing Market Size & Trend Analysis, by Product & Service, 2018 to 2030 (USD Million)
• 4.4. Instruments
  • 4.4.1. Instruments Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 4.5. Kits & Reagents
  • 4.5.1. Kits & Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5.2. Bisulfite Conversion Kits & Reagents
    • 4.5.2.1. Bisulfite Conversion Kits & Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5.3. Library Preparation Kits & Reagents
    • 4.5.3.1. Library Preparation Kits & Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5.4. DNA Extraction & Purification Kits & Reagents
    • 4.5.4.1. DNA Extraction & Purification Kits & Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5.5. PCR & Amplification Kits & Reagents
    • 4.5.5.1. PCR & Amplification Kits & Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5.6. Sequencing Kits & Reagents
    • 4.5.6.1. Sequencing Kits & Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5.7. Others
    • 4.5.7.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 4.6. Services
  • 4.6.1. Services Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 5. Whole Genome Bisulfite Sequencing Market: Workflow Estimates & Trend Analysis

• 5.1. Workflow Segment Dashboard
• 5.2. Global Whole Genome Bisulfite Sequencing Market Workflow Movement Analysis
• 5.3. Global Whole Genome Bisulfite Sequencing Market Size & Trend Analysis, by Workflow, 2018 to 2030 (USD Million)
• 5.4. Sample Preparation & Bisulfite Conversion
  • 5.4.1. Sample Preparation & Bisulfite Conversion Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 5.5. Library Preparation & Amplification
  • 5.5.1. Library Preparation & Amplification Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 5.6. Sequencing
  • 5.6.1. Sequencing Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 5.7. Data Analysis & Interpretation
  • 5.7.1. Data Analysis & Interpretation Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 6. Whole Genome Bisulfite Sequencing Market: Application Estimates & Trend Analysis

• 6.1. Application Segment Dashboard
• 6.2. Global Whole Genome Bisulfite Sequencing Market Application Movement Analysis
• 6.3. Global Whole Genome Bisulfite Sequencing Market Size & Trend Analysis, by Application, 2018 to 2030 (USD Million)
• 6.4. Drug Development
  • 6.4.1. Drug Development Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 6.5. Stem Cell Research
  • 6.5.1. Stem Cell Research Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 6.6. Developmental Biology
  • 6.6.1. Developmental Biology Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 6.7. Others
  • 6.7.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 7. Whole Genome Bisulfite Sequencing Market: End Use Estimates & Trend Analysis

• 7.1. End Use Segment Dashboard
• 7.2. Global Whole Genome Bisulfite Sequencing Market End Use Movement Analysis
• 7.3. Global Whole Genome Bisulfite Sequencing Market Size & Trend Analysis, by End Use, 2018 to 2030 (USD Million)
• 7.4. Academic & Research Institutes
  • 7.4.1. Academic & Research Institutes Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.5. Pharmaceutical & Biotechnological Companies
  • 7.5.1. Pharmaceutical & Biotechnological Companies Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.6. Others
  • 7.6.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 8. Whole Genome Bisulfite Sequencing Market: Regional Estimates & Trend Analysis

• 8.1. Regional Market Share Analysis, 2024 & 2030
• 8.2. Regional Market Dashboard
• 8.3. Market Size & Forecasts and Trend Analysis, 2018 to 2030
• 8.4. North America
  • 8.4.1. North America Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.4.2. U.S.
    • 8.4.2.1. Key Country Dynamics
    • 8.4.2.2. Competitive Scenario
    • 8.4.2.3. Regulatory Framework
    • 8.4.2.4. U.S. Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.4.3. Canada
    • 8.4.3.1. Key Country Dynamics
    • 8.4.3.2. Competitive Scenario
    • 8.4.3.3. Regulatory Framework
    • 8.4.3.4. Canada Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.4.4. Mexico
    • 8.4.4.1. Key Country Dynamics
    • 8.4.4.2. Competitive Scenario
    • 8.4.4.3. Regulatory Framework
    • 8.4.4.4. Mexico Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 8.5. Europe
  • 8.5.1. Europe Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.2. UK
    • 8.5.2.1. Key Country Dynamics
    • 8.5.2.2. Competitive Scenario
    • 8.5.2.3. Regulatory Framework
    • 8.5.2.4. UK Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.3. Germany
    • 8.5.3.1. Key Country Dynamics
    • 8.5.3.2. Competitive Scenario
    • 8.5.3.3. Regulatory Framework
    • 8.5.3.4. Germany Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.4. France
    • 8.5.4.1. Key Country Dynamics
    • 8.5.4.2. Competitive Scenario
    • 8.5.4.3. Regulatory Framework
    • 8.5.4.4. France Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.5. Italy
    • 8.5.5.1. Key Country Dynamics
    • 8.5.5.2. Competitive Scenario
    • 8.5.5.3. Regulatory Framework
    • 8.5.5.4. Italy Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.6. Spain
    • 8.5.6.1. Key Country Dynamics
    • 8.5.6.2. Competitive Scenario
    • 8.5.6.3. Regulatory Framework
    • 8.5.6.4. Spain Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.7. Denmark
    • 8.5.7.1. Key Country Dynamics
    • 8.5.7.2. Competitive Scenario
    • 8.5.7.3. Regulatory Framework
    • 8.5.7.4. Denmark Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.8. Sweden
    • 8.5.8.1. Key Country Dynamics
    • 8.5.8.2. Competitive Scenario
    • 8.5.8.3. Regulatory Framework
    • 8.5.8.4. Sweden Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5.9. Norway
    • 8.5.9.1. Key Country Dynamics
    • 8.5.9.2. Competitive Scenario
    • 8.5.9.3. Regulatory Framework
    • 8.5.9.4. Norway Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 8.6. Asia Pacific
  • 8.6.1. Asia Pacific Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6.2. Japan
    • 8.6.2.1. Key Country Dynamics
    • 8.6.2.2. Competitive Scenario
    • 8.6.2.3. Regulatory Framework
    • 8.6.2.4. Japan Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6.3. China
    • 8.6.3.1. Key Country Dynamics
    • 8.6.3.2. Competitive Scenario
    • 8.6.3.3. Regulatory Framework
    • 8.6.3.4. China Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6.4. India
    • 8.6.4.1. Key Country Dynamics
    • 8.6.4.2. Competitive Scenario
    • 8.6.4.3. Regulatory Framework
    • 8.6.4.4. India Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6.5. Australia
    • 8.6.5.1. Key Country Dynamics
    • 8.6.5.2. Competitive Scenario
    • 8.6.5.3. Regulatory Framework
    • 8.6.5.4. Australia Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6.6. Thailand
    • 8.6.6.1. Key Country Dynamics
    • 8.6.6.2. Competitive Scenario
    • 8.6.6.3. Regulatory Framework
    • 8.6.6.4. Thailand Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6.7. South Korea
    • 8.6.7.1. Key Country Dynamics
    • 8.6.7.2. Competitive Scenario
    • 8.6.7.3. Regulatory Framework
    • 8.6.7.4. South Korea Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 8.7. Latin America
  • 8.7.1. Latin America Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.7.2. Brazil
    • 8.7.2.1. Key Country Dynamics
    • 8.7.2.2. Competitive Scenario
    • 8.7.2.3. Regulatory Framework
    • 8.7.2.4. Brazil Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.7.3. Argentina
    • 8.7.3.1. Key Country Dynamics
    • 8.7.3.2. Competitive Scenario
    • 8.7.3.3. Regulatory Framework
    • 8.7.3.4. Argentina Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 8.8. MEA
  • 8.8.1. MEA Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.8.2. South Africa
    • 8.8.2.1. Key Country Dynamics
    • 8.8.2.2. Competitive Scenario
    • 8.8.2.3. Regulatory Framework
    • 8.8.2.4. South Africa Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.8.3. Saudi Arabia
    • 8.8.3.1. Key Country Dynamics
    • 8.8.3.2. Competitive Scenario
    • 8.8.3.3. Regulatory Framework
    • 8.8.3.4. Saudi Arabia Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.8.4. UAE
    • 8.8.4.1. Key Country Dynamics
    • 8.8.4.2. Competitive Scenario
    • 8.8.4.3. Regulatory Framework
    • 8.8.4.4. UAE Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.8.5. Kuwait
    • 8.8.5.1. Key Country Dynamics
    • 8.8.5.2. Competitive Scenario
    • 8.8.5.3. Regulatory Framework
    • 8.8.5.4. Kuwait Whole Genome Bisulfite Sequencing Market Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 9. Competitive Landscape

• 9.1. Participant Categorization
• 9.2. Company Market Position Analysis, 2024
• 9.3. Participant's Overview
  • 9.3.1. Thermo Fisher Scientific, Inc.
    • 9.3.1.1. Participant's Overview
    • 9.3.1.2. Financial Performance
    • 9.3.1.3. Product/Service Benchmarking
    • 9.3.1.4. Strategic Initiatives
  • 9.3.2. Illumina, Inc.
    • 9.3.2.1. Participant's Overview
    • 9.3.2.2. Financial Performance
    • 9.3.2.3. Product/Service Benchmarking
    • 9.3.2.4. Strategic Initiatives
  • 9.3.3. Danaher
    • 9.3.3.1. Participant's Overview
    • 9.3.3.2. Financial Performance
    • 9.3.3.3. Product/Service Benchmarking
    • 9.3.3.4. Strategic Initiatives
  • 9.3.4. Merck KGaA
    • 9.3.4.1. Participant's Overview
    • 9.3.4.2. Financial Performance
    • 9.3.4.3. Product/Service Benchmarking
    • 9.3.4.4. Strategic Initiatives
  • 9.3.5. Zymo Research
    • 9.3.5.1. Participant's Overview
    • 9.3.5.2. Financial Performance
    • 9.3.5.3. Product/Service Benchmarking
    • 9.3.5.4. Strategic Initiatives
  • 9.3.6. QIAGEN
    • 9.3.6.1. Participant's Overview
    • 9.3.6.2. Financial Performance
    • 9.3.6.3. Product/Service Benchmarking
    • 9.3.6.4. Strategic Initiatives
  • 9.3.7. Agilent Technologies
    • 9.3.7.1. Participant's Overview
    • 9.3.7.2. Financial Performance
    • 9.3.7.3. Product/Service Benchmarking
    • 9.3.7.4. Strategic Initiatives
  • 9.3.8. BGI
    • 9.3.8.1. Participant's Overview
    • 9.3.8.2. Financial Performance
    • 9.3.8.3. Product/Service Benchmarking
    • 9.3.8.4. Strategic Initiatives
  • 9.3.9. Hologic Inc.
    • 9.3.9.1. Participant's Overview
    • 9.3.9.2. Financial Performance
    • 9.3.9.3. Product/Service Benchmarking
    • 9.3.9.4. Strategic Initiatives
  • 9.3.10. New England Biolabs
    • 9.3.10.1. Participant's Overview
    • 9.3.10.2. Financial Performance
    • 9.3.10.3. Product/Service Benchmarking
    • 9.3.10.4. Strategic Initiatives