다운스트림 프로세싱 시장 규모, 점유율, 동향 분석 보고서 : 제품별, 기술별, 용도별, 지역별, 부문별 예측(2025-2030년)

Downstream Processing Market Growth & Trends:

The global downstream processing market size is anticipated to reach USD 94.79 billion by 2030, according to a new report by Grand View Research, Inc. The market is projected to grow at a CAGR of 14.49% from 2025 to 2030. The capacity requirements during the development of biologic drugs have changed over the past few years, wherein the demand for manufacturing high-volume products has shifted to developing small-volume, high-potency products. This creates new avenues for single-use technologies. A rise in the utilization of downstream processing techniques for the development of COVID-19 vaccines is a significant factor driving the market. The adoption of small-scale, single-use systems for process development and downstream processing is already high.

Thus, evolutionary changes are expected in the area of single-use technologies for manufacturing small-volume, highly-potent drugs. The development of novel film chemistries, closed systems, automation in clinical-scale single-use systems, and smart sensors are some noteworthy advancements in the field. A rise in applications of downstream processing for the production of biopharmaceuticals is expected to bring growth opportunities to the market. This has also led to an increase in strategic deals and development in the market. For instance, in February 2021, Evozyne, LLC collaborated with a leading rare disorders drug manufacturer for the production and marketing of novel biopharmaceuticals for immune modulation.

Key players are investing in the bioprocessing of vaccines and therapies for COVID-19 to increase their market share. For instance, in May 2022, Lonza and ALSA Ventures are partnering to provide biotech firms with development and manufacturing services. In May 2022, Lonza added Titanium Dioxide-free white hard gelatin capsules to its Capsugel Capsule Line. The new capsule includes an alternative opacifying technology that provides a good masking solution as well as enhanced light protection for the fill formulation. In December 2021, Repligen bought Newton, New Jersey-based BioFlex Solutions. The purchase adds to and enhances Repligen's single-use fluid management product line, as well as simplifies its supply chain. The integration of BioFlex Solutions strengthens its system offering by further integrating components and assemblies.

Downstream Processing Market Report Highlights:

• The chromatography systems segment dominated the market for downstream processing and accounted for the largest revenue share of 41.43% in 2024
• The advent of single-use chromatography systems that bring an 80.0% reduction of the use of water and chemicals for buffer has further increased the adoption of chromatography for downstream processing of bio-therapeutics
• Filters are anticipated to grow at a lucrative rate over the forecast period. Efforts undertaken by the key players to develop intelligent membranes for purification & separation is fuelling the market growth
• Purification by chromatography accounted for the largest revenue share as it can be employed across all steps of a downstream process. The technique is also crucial in bioprocessing to obtain pure biologics
• The antibiotic production segment dominated the market for downstream processing and generated the largest revenue share of 29.84% in 2024 owing to the wide applications of antibiotics for the treatment of several disorders.
• A rise in occurrences of antibiotic resistance also propels the industrial-scale development of novel antibiotic candidates
• North America dominated the market for downstream processing with the largest revenue share of 34.57% in 2022 owing to government support for promoting bioprocess technologies, rising medical expenditure, and developed healthcare infrastructure.
• Asia Pacific expected to register the highest growth rate of 15.67% during 2023-2030 due to a rise in contract development services in emerging economies

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Market Segmentation and Scope
• 1.2. Segment Definitions
  • 1.2.1. Product
  • 1.2.2. Technique
  • 1.2.3. Application
• 1.3. Research Methodology
• 1.4. Information Procurement
• 1.5. Information or Data Analysis
  • 1.5.1. Data analysis models
• 1.6. Market Formulation & Validation
• 1.7. List of Secondary Sources
• 1.8. List of Primary Sources
• 1.9. Objectives

Chapter 2. Executive Summary

• 2.1. Market Snapshot
• 2.2. Segment Snapshot
• 2.3. Competitive Landscape Snapshot

Chapter 3. Market Variables and Trends

• 3.1. Market Lineage Outlook
  • 3.1.1. Parent Market Outlook
  • 3.1.2. Related/Ancillary Market Outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
    • 3.2.1.1. Commercial Success Of Biopharmaceuticals Boosts Demand For Innovation In Bioprocessing
    • 3.2.1.2. Rising Adoption Of Single-Use Technology In Bioprocessing
    • 3.2.1.3. Environmental Advantage
    • 3.2.1.4. Operating And Construction Cost Advantage
    • 3.2.1.5. Flexibility Advantage
    • 3.2.1.6. Time Advantage
    • 3.2.1.7. Expansion Of Bioprocessing Capacity
  • 3.2.2. Market Restraint Analysis
    • 3.2.2.1. High Cost
    • 3.2.2.2. Dearth Of Skilled Professionals
• 3.3. Industry Analysis Tools
  • 3.3.1. Porter's Five Forces Analysis
  • 3.3.2. PESTEL Analysis
  • 3.3.3. COVID-19 Impact Analysis

Chapter 4. Product Business Analysis

• 4.1. Product Segment Dashboard
• 4.2. Downstream Processing Market: Product Movement Analysis
• 4.3. Chromatography Systems
  • 4.3.1. Chromatography Systems Market, 2018 - 2030 (USD Million)
• 4.4. Filters
  • 4.4.1. Filters Market, 2018 - 2030 (USD Million)
• 4.5. Evaporators
  • 4.5.1. Evaporators Market, 2018 - 2030 (USD Million)
• 4.6. Centrifuges
  • 4.6.1. Centrifuges Market, 2018 - 2030 (USD Million)
• 4.7. Dryers
  • 4.7.1. Dryers Market, 2018 - 2030 (USD Million)
• 4.8. Others
  • 4.8.1. Other Products Market, 2018 - 2030 (USD Million)

Chapter 5. Technique Business Analysis

• 5.1. Technique Segment Dashboard
• 5.2. Downstream Processing Market: Technique Movement Analysis
• 5.3. Cell Disruption
  • 5.3.1. Cell Disruption Market, 2018 - 2030 (USD Million)
• 5.4. Solid-liquid Separation
  • 5.4.1. Solid-liquid Separation Market, 2018 - 2030 (USD Million)
  • 5.4.2. Filtration
    • 5.4.2.1. Filtration Market, 2018 - 2030 (USD Million)
  • 5.4.3. Centrifugation
    • 5.4.3.1. Centrifugation Market, 2018 - 2030 (USD Million)
• 5.5. Concentration
  • 5.5.1. Concentration Market, 2018 - 2030 (USD Million)
  • 5.5.2. Evaporation
    • 5.5.2.1. Evaporation Market, 2018 - 2030 (USD Million)
  • 5.5.3. Membrane Filtration
    • 5.5.3.1. Membrane Filtration Market, 2018 - 2030 (USD Million)
• 5.6. Purification By Chromatography
  • 5.6.1. Purification By Chromatography Market, 2018 - 2030 (USD Million)
• 5.7. Formulation
  • 5.7.1. Formulation Market, 2018 - 2030 (USD Million)

Chapter 6. Application Business Analysis

• 6.1. Application Segment Dashboard
• 6.2. Downstream Processing Market: Application Movement Analysis
• 6.3. Antibiotic Production
  • 6.3.1. Antibiotic Production Market, 2018 - 2030 (USD Million)
• 6.4. Hormone Production
  • 6.4.1. Hormone Production Market, 2018 - 2030 (USD Million)
• 6.5. Antibodies Production
  • 6.5.1. Antibodies Production Market, 2018 - 2030 (USD Million)
• 6.6. Enzyme Production
  • 6.6.1. Enzyme Production Market, 2018 - 2030 (USD Million)
• 6.7. Vaccine Production
  • 6.7.1. Vaccine Production Market, 2018 - 2030 (USD Million)

Chapter 7. Regional Business Analysis

• 7.1. Regional Dashboard
• 7.2. Downstream Processing Market Share By Region, 2024 & 2030
• 7.3. North America
  • 7.3.1. North America Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.3.2. U.S.
    • 7.3.2.1. Key Country Dynamics
    • 7.3.2.2. Competitive Scenario
    • 7.3.2.3. Regulatory Framework
    • 7.3.2.4. U.S. Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.3.3. Canada
    • 7.3.3.1. Key Country Dynamics
    • 7.3.3.2. Competitive Scenario
    • 7.3.3.3. Regulatory Framework
    • 7.3.3.4. Canada Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.3.4. Mexico
    • 7.3.4.1. Key Country Dynamics
    • 7.3.4.2. Competitive Scenario
    • 7.3.4.3. Regulatory Framework
    • 7.3.4.4. Mexico Downstream Processing Market, 2018 - 2030 (USD Million)
• 7.4. Europe
  • 7.4.1. Europe Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.2. UK
    • 7.4.2.1. Key Country Dynamics
    • 7.4.2.2. Competitive Scenario
    • 7.4.2.3. Regulatory Framework
    • 7.4.2.4. UK Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.3. Germany
    • 7.4.3.1. Key Country Dynamics
    • 7.4.3.2. Competitive Scenario
    • 7.4.3.3. Regulatory Framework
    • 7.4.3.4. Germany Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.4. France
    • 7.4.4.1. Key Country Dynamics
    • 7.4.4.2. Competitive Scenario
    • 7.4.4.3. Regulatory Framework
    • 7.4.4.4. France Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.5. Italy
    • 7.4.5.1. Key Country Dynamics
    • 7.4.5.2. Competitive Scenario
    • 7.4.5.3. Regulatory Framework
    • 7.4.5.4. Italy Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.6. Spain
    • 7.4.6.1. Key Country Dynamics
    • 7.4.6.2. Competitive Scenario
    • 7.4.6.3. Regulatory Framework
    • 7.4.6.4. Spain Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.7. Denmark
    • 7.4.7.1. Key Country Dynamics
    • 7.4.7.2. Competitive Scenario
    • 7.4.7.3. Regulatory Framework
    • 7.4.7.4. Denmark Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.8. Sweden
    • 7.4.8.1. Key Country Dynamics
    • 7.4.8.2. Competitive Scenario
    • 7.4.8.3. Regulatory Framework
    • 7.4.8.4. Sweden Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.4.9. Norway
    • 7.4.9.1. Key Country Dynamics
    • 7.4.9.2. Competitive Scenario
    • 7.4.9.3. Regulatory Framework
    • 7.4.9.4. Norway Downstream Processing Market, 2018 - 2030 (USD Million)
• 7.5. Asia Pacific
  • 7.5.1. Asia Pacific Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.5.2. Japan
    • 7.5.2.1. Key Country Dynamics
    • 7.5.2.2. Competitive Scenario
    • 7.5.2.3. Regulatory Framework
    • 7.5.2.4. Japan Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.5.3. China
    • 7.5.3.1. Key Country Dynamics
    • 7.5.3.2. Competitive Scenario
    • 7.5.3.3. Regulatory Framework
    • 7.5.3.4. China Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.5.4. India
    • 7.5.4.1. Key Country Dynamics
    • 7.5.4.2. Competitive Scenario
    • 7.5.4.3. Regulatory Framework
    • 7.5.4.4. India Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.5.5. Australia
    • 7.5.5.1. Key Country Dynamics
    • 7.5.5.2. Competitive Scenario
    • 7.5.5.3. Regulatory Framework
    • 7.5.5.4. Australia Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.5.6. Thailand
    • 7.5.6.1. Key Country Dynamics
    • 7.5.6.2. Competitive Scenario
    • 7.5.6.3. Regulatory Framework
    • 7.5.6.4. Thailand Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.5.7. South Korea
    • 7.5.7.1. Key Country Dynamics
    • 7.5.7.2. Competitive Scenario
    • 7.5.7.3. Regulatory Framework
    • 7.5.7.4. South Korea Downstream Processing Market, 2018 - 2030 (USD Million)
• 7.6. Latin America
  • 7.6.1. Latin America Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.6.2. Brazil
    • 7.6.2.1. Key Country Dynamics
    • 7.6.2.2. Competitive Scenario
    • 7.6.2.3. Regulatory Framework
    • 7.6.2.4. Brazil Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.6.3. Argentina
    • 7.6.3.1. Key Country Dynamics
    • 7.6.3.2. Competitive Scenario
    • 7.6.3.3. Regulatory Framework
    • 7.6.3.4. Argentina Downstream Processing Market, 2018 - 2030 (USD Million)
• 7.7. MEA
  • 7.7.1. MEA Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.7.2. South Africa
    • 7.7.2.1. Key Country Dynamics
    • 7.7.2.2. Competitive Scenario
    • 7.7.2.3. Regulatory Framework
    • 7.7.2.4. South Africa Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.7.3. Saudi Arabia
    • 7.7.3.1. Key Country Dynamics
    • 7.7.3.2. Competitive Scenario
    • 7.7.3.3. Regulatory Framework
    • 7.7.3.4. Saudi Arabia Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.7.4. UAE
    • 7.7.4.1. Key Country Dynamics
    • 7.7.4.2. Competitive Scenario
    • 7.7.4.3. Regulatory Framework
    • 7.7.4.4. UAE Downstream Processing Market, 2018 - 2030 (USD Million)
  • 7.7.5. Kuwait
    • 7.7.5.1. Key Country Dynamics
    • 7.7.5.2. Competitive Scenario
    • 7.7.5.3. Regulatory Framework
    • 7.7.5.4. Kuwait Downstream Processing Market, 2018 - 2030 (USD Million)

Chapter 8. Competitive Landscape

• 8.1. Company Categorization
• 8.2. Strategy Mapping
• 8.3. Company Market Position Analysis, 2024
• 8.4. Company Profiles/Listing
  • 8.4.1. Merck KGaA
    • 8.4.1.1. Overview
    • 8.4.1.2. Financial Performance
    • 8.4.1.3. Product Benchmarking
    • 8.4.1.4. Strategic Initiatives
  • 8.4.2. Sartorius Stedim Biotech
    • 8.4.2.1. Overview
    • 8.4.2.2. Financial Performance
    • 8.4.2.3. Product Benchmarking
    • 8.4.2.4. Strategic Initiatives
  • 8.4.3. Thermo Fisher Scientific, Inc.
    • 8.4.3.1. Overview
    • 8.4.3.2. Financial Performance
    • 8.4.3.3. Product Benchmarking
    • 8.4.3.4. Strategic Initiatives
  • 8.4.4. Danaher
    • 8.4.4.1. Overview
    • 8.4.4.2. Financial Performance
    • 8.4.4.3. Product Benchmarking
    • 8.4.4.4. Strategic Initiatives
  • 8.4.5. Repligen
    • 8.4.5.1. Overview
    • 8.4.5.2. Financial Performance
    • 8.4.5.3. Product Benchmarking
    • 8.4.5.4. Strategic Initiatives
  • 8.4.6. 3M Company
    • 8.4.6.1. Overview
    • 8.4.6.2. Financial Performance
    • 8.4.6.3. Product Benchmarking
    • 8.4.6.4. Strategic Initiatives
  • 8.4.7. Corning Corporation
    • 8.4.7.1. Overview
    • 8.4.7.2. Financial Performance
    • 8.4.7.3. Product Benchmarking
    • 8.4.7.4. Strategic Initiatives
  • 8.4.8. Lonza Group Ltd
    • 8.4.8.1. Overview
    • 8.4.8.2. Financial Performance
    • 8.4.8.3. Product Benchmarking
    • 8.4.8.4. Strategic Initiatives
  • 8.4.9. Dover Corporation
    • 8.4.9.1. Overview
    • 8.4.9.2. Financial Performance
    • 8.4.9.3. Product Benchmarking
    • 8.4.9.4. Strategic Initiatives
  • 8.4.10. Eppendorf A
    • 8.4.10.1. Overview
    • 8.4.10.2. Financial Performance
    • 8.4.10.3. Product Benchmarking
    • 8.4.10.4. Strategic Initiatives