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U.S. Next-generation Sequencing Library Preparation Market Size, Share & Trends Analysis Report By Sequencing Type (Targeted Genome Sequencing, Whole Genome Sequencing), By Product, By Application, By End Use, And Segment Forecasts, 2025 - 2033

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    • Illumina, Inc.
    • Agilent Technologies, Inc.
    • F. Hoffmann-La Roche AG, Inc.
    • BD
    • Oxford Nanopore Technologies
    • New England Biolabs Inc.
    • Revvity, Inc.
    • QIAGEN NV
    • Pacific Biosciences of California, Inc.
    • Thermo Fisher Scientific Inc.
KSA 25.08.26

U.S. Next-generation Sequencing Library Preparation Market Summary

The U.S. next-generation sequencing library preparation market size was estimated at USD 652.2 million in 2024 and is projected to reach USD 1.96 billion by 2033, growing at a CAGR of 13.09% from 2025 to 2033. Rapid advancements in sequencing technologies and bioinformatics have facilitated the detection of DNA variations.

Additionally, the broad adoption of Next-Generation Sequencing (NGS) and Whole-Genome Sequencing (WGS) allows for the simultaneous analysis of numerous genes on a single platform, enhancing the role of DNA sequencing in clinical diagnostics. These developments are anticipated to significantly propel market growth over the forecast period.

U.S. Next-generation Sequencing Library Preparation Market Report Segmentation

This report forecasts revenue growth at the country level and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the U.S. next-generation sequencing library preparation market report based on sequencing type, product, application, end use, and region:

  • Sequencing Type Outlook (Revenue, USD Million, 2021 - 2033)
  • Targeted Genome Sequencing
  • Whole Genome Sequencing
  • Whole Exome Sequencing
  • Other Sequencing Types
  • Product Outlook (Revenue, USD Million, 2021 - 2033)
  • Reagents & Consumables
    • DNA Library Preparation Kits
    • RNA Library Preparation Kits
    • Other Reagents & Consumables
  • Instruments
  • Application Outlook (Revenue, USD Million, 2021 - 2033)
  • Drug & Biomarker Discovery
  • Disease Diagnostics
    • Cancer Diagnostics
    • Reproductive Health Diagnostics
    • Infectious Disease Diagnostics
    • Other Disease Diagnostic Applications
  • Others
  • End Use Outlook (Revenue, USD Million, 2021 - 2033)
  • Hospitals and Clinics
  • Academic and Research Institutions
  • Pharmaceutical and Biotechnology Companies
  • Others

Table of Contents

Chapter 1. Methodology and Scope

  • 1.1. Market Segmentation & Scope
  • 1.2. Market Definitions
    • 1.2.1. Sequencing Type Segment
    • 1.2.2. Product Segment
    • 1.2.3. Application Segment
    • 1.2.4. End Use Segment
  • 1.3. Information analysis
    • 1.3.1. Market formulation & data visualization
  • 1.4. Data validation & publishing
  • 1.5. Information Procurement
    • 1.5.1. Primary Research
  • 1.6. Information or Data Analysis
  • 1.7. Market Formulation & Validation
  • 1.8. Market Model
  • 1.9. Total Market: CAGR Calculation
  • 1.10. Objectives

Chapter 2. Executive Summary

  • 2.1. Market Outlook
  • 2.2. Segmental Snapshot
  • 2.3. Competitive Landscape Snapshot

Chapter 3. Market Variables, Trends, and Scope

  • 3.1. Market Lineage
    • 3.1.1. Parent Market Analysis
    • 3.1.2. Ancillary Market Analysis
  • 3.2. U.S. Next-generation Sequencing Library Preparation Market - Market Dynamics
    • 3.2.1. Market Driver Analysis
    • 3.2.2. Market Restraint Analysis
  • 3.3. Market Analysis Tools
    • 3.3.1. Porter's Five Forces Analysis
    • 3.3.2. SWOT Analysis, By Factor (Political & Legal, Economic And Technological)
    • 3.3.3. COVID-19 Impact Analysis

Chapter 4. U.S. Next-generation Sequencing Library Preparation Market: Sequencing Type Business Analysis

  • 4.1. Sequencing Type Segment Dashboard
  • 4.2. U.S. Next-generation Sequencing Library Preparation Market Sequencing Type Movement Analysis, 2024 & 2033
  • 4.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by Sequencing Type, 2021 to 2033 (USD Million)
  • 4.4. Targeted Genome Sequencing
    • 4.4.1. Targeted Genome Sequencing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 4.5. Whole Genome Sequencing
    • 4.5.1. Whole Genome Sequencing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 4.6. Whole Exome Sequencing
    • 4.6.1. Whole Exome Sequencing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 4.7. Other Sequencing Types
    • 4.7.1. Other Sequencing Types Market Estimates And Forecasts, 2021 - 2033 (USD Million)

Chapter 5. U.S. Next-generation Sequencing Library Preparation Market: Product Business Analysis

  • 5.1. Product Segment Dashboard
  • 5.2. U.S. Next-generation Sequencing Library Preparation Market Product Movement Analysis, 2024 & 2033
  • 5.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by Product, 2021 to 2033 (USD Million)
  • 5.4. Reagents & Consumables
    • 5.4.1. Reagents & Consumables Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 5.4.2. DNA Library Preparation Kits
      • 5.4.2.1. DNA Library Preparation Kits Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 5.4.3. RNA Library Preparation Kits
      • 5.4.3.1. RNA Library Preparation Kits Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 5.4.4. Other Reagents & Consumables
      • 5.4.4.1. Other Reagents & Consumables Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 5.5. Instruments
    • 5.5.1. Instruments Market Estimates And Forecasts, 2021 - 2033 (USD Million)

Chapter 6. U.S. Next-generation Sequencing Library Preparation Market: Application Business Analysis

  • 6.1. Application Segment Dashboard
  • 6.2. U.S. Next-generation Sequencing Library Preparation Market Application Movement Analysis, 2024 & 2033
  • 6.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million)
  • 6.4. Drug & Biomarker Discovery
    • 6.4.1. Drug & Biomarker Discovery Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 6.5. Disease Diagnostics
    • 6.5.1. Disease Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 6.5.2. Cancer Diagnostics
      • 6.5.2.1. Cancer Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 6.5.3. Reproductive Health Diagnostics
      • 6.5.3.1. Reproductive Health Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 6.5.4. Infectious Disease Diagnostics
      • 6.5.4.1. Infectious Disease Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
    • 6.5.5. Other Disease Diagnostic Applications
      • 6.5.5.1. Other Disease Diagnostic Applications Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 6.6. Others
    • 6.6.1. Others Market Estimates And Forecasts, 2021 - 2033 (USD Million)

Chapter 7. U.S. Next-generation Sequencing Library Preparation Market: End Use Business Analysis

  • 7.1. End Use Segment Dashboard
  • 7.2. U.S. Next-generation Sequencing Library Preparation Market End Use Movement Analysis, 2024 & 2033
  • 7.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
  • 7.4. Hospitals and Clinics
    • 7.4.1. Hospitals and Clinics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 7.5. Academic and Research Institutions
    • 7.5.1. Academic and Research Institutions Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 7.6. Pharmaceutical and Biotechnology Companies
    • 7.6.1. Pharmaceutical and Biotechnology Companies Market Estimates And Forecasts, 2021 - 2033 (USD Million)
  • 7.7. Others
    • 7.7.1. Others Market Estimates And Forecasts, 2021 - 2033 (USD Million)

Chapter 8. Competitive Landscape

  • 8.1. Company/Competition Categorization
  • 8.2. Strategy Mapping
  • 8.3. Company Market Position Analysis, 2024
  • 8.4. Company Profiles/Listing
    • 8.4.1. Illumina, Inc.
      • 8.4.1.1. Company overview
      • 8.4.1.2. Financial performance
      • 8.4.1.3. Product benchmarking
      • 8.4.1.4. Strategic initiatives
    • 8.4.2. Agilent Technologies, Inc.
      • 8.4.2.1. Company overview
      • 8.4.2.2. Financial performance
      • 8.4.2.3. Product benchmarking
      • 8.4.2.4. Strategic initiatives
    • 8.4.3. F. Hoffmann-La Roche AG, Inc.
      • 8.4.3.1. Company overview
      • 8.4.3.2. Financial performance
      • 8.4.3.3. Product benchmarking
      • 8.4.3.4. Strategic initiatives
    • 8.4.4. BD
      • 8.4.4.1. Company overview
      • 8.4.4.2. Financial performance
      • 8.4.4.3. Product benchmarking
      • 8.4.4.4. Strategic initiatives
    • 8.4.5. Oxford Nanopore Technologies
      • 8.4.5.1. Company overview
      • 8.4.5.2. Financial performance
      • 8.4.5.3. Product benchmarking
      • 8.4.5.4. Strategic initiatives
    • 8.4.6. New England Biolabs Inc.
      • 8.4.6.1. Company overview
      • 8.4.6.2. Financial performance
      • 8.4.6.3. Product benchmarking
      • 8.4.6.4. Strategic initiatives
    • 8.4.7. Revvity, Inc.
      • 8.4.7.1. Company overview
      • 8.4.7.2. Financial performance
      • 8.4.7.3. Product benchmarking
      • 8.4.7.4. Strategic initiatives
    • 8.4.8. QIAGEN N.V.
      • 8.4.8.1. Company overview
      • 8.4.8.2. Financial performance
      • 8.4.8.3. Product benchmarking
      • 8.4.8.4. Strategic initiatives
    • 8.4.9. Pacific Biosciences of California, Inc.
      • 8.4.9.1. Company overview
      • 8.4.9.2. Financial performance
      • 8.4.9.3. Product benchmarking
      • 8.4.9.4. Strategic initiatives
    • 8.4.10. Thermo Fisher Scientific Inc.
      • 8.4.10.1. Company overview
      • 8.4.10.2. Financial performance
      • 8.4.10.3. Product benchmarking
      • 8.4.10.4. Strategic initiatives
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