DNA 합성 기술 및 서비스 시장 : 합성 방법별, 주요 응용 분야별, 기업 규모별, 주요 지역별

DNA SYNTHESIS TECHNOLOGIES AND SERVICES MARKET: OVERVIEW

As per Roots Analysis, the global DNA synthesis technologies and services market is estimated to grow from USD 1.20 billion in the current year to USD 8.6 billion by 2035, at a CAGR of 21.6% during the forecast period, till 2035.

The market sizing and opportunity analysis has been segmented across the following parameters:

Method of DNA Synthesis

• Chemical Method
• Enzymatic Method

Key Applications Areas

• Research & Diagnostics
• Therapeutics

Company Size

• Small
• Mid-Sized
• Large

Key Geographical Regions

• North America
• Europe
• Asia-Pacific
• Rest of the World

DNA SYNTHESIS TECHNOLOGIES AND SERVICES MARKET: GROWTH AND TRENDS

The concept of artificial DNA synthesis has a far-reaching impact across multiple areas, including genetic circuit design, genetic engineering, genome synthesis, diagnosis and treatment of genetic diseases. It is worth mentioning that synthetic biology has emerged as a disruptive technology, capable of delivering new solutions to global healthcare, agriculture, manufacturing and environmental challenges. Moreover, the recent advancements in the field of molecular biology, such as the development of automatic robust chemistries (used for chemical synthesis of DNA) have contributed towards the engineering of biological systems by enabling high-throughput study genomes. Synthetic biology, when combined with sequenced data generated by next generation sequencing (NGS) technology, allows quantitative analysis of RNA and DNA to study the genetic variations associated with the disease or other biological phenomena.

Notably, the spread of the COVID-19 in the past few years has given a significant boost to the development of DNA and RNA-based vaccines to induce potent immune responses in patients. Moreover, customized DNA and RNA synthesis coupled with CRISPR technologies for gene editing and other synthetic biology technologies have demonstrated the potential to change the standard of care for a wide range of disease indications. DNA synthesis technologies not only facilitate parallelized synthesis of DNA but also provide unmatched precision, scalability and speed.

Several companies have developed proprietary enzymatic DNA synthesis platforms offering distinct advantages (such as the potential to increase the length of DNA fragments, greater accessibility and convenience) over conventional DNA synthesis methods. Furthermore, a significant proportion of medical researchers and drug developers prefer to outsource DNA synthesis and replication operations to third-party platforms / service providers who claim to provide expertise in DNA synthesis and production. Given the rising need for DNA across a wide range of applications, we are led to believe that the DNA synthesis and DNA replication platforms and services industry is likely to witness noteworthy market growth during the forecast period.

DNA SYNTHESIS TECHNOLOGIES AND SERVICES MARKET: KEY INSIGHTS

The report delves into the current state of the DNA synthesis technologies and services market and identifies potential growth opportunities within the industry. Some key findings from the report include:

• Around 65 companies presently claim to have the required expertise for DNA synthesis technologies and affiliated services; of these, more than 50% of players are small companies and have recently been established.
• These technology and service providers claim to employ different cost-effective methods for the synthesis of DNA, having applications in various biomedical fields.
• There has been a notable increase in the published scientific literature related to DNA synthesis technologies and services in the last few years; such articles have been published in over 50 countries.

• The growing interest in DNA synthesis technologies and services is reflected by the increase in partnership activity in the recent past; in fact, between 2019 and 2021, the partnership activity increased at a CAGR of 18%.
• Over the past few years, 150 academic grants have been awarded to various organizations in order to support the ongoing efforts related to research and innovation in the field of DNA synthesis technologies.
• Several investors, having realized the future opportunity associated with the DNA synthesis technologies and services market, have invested more than USD 750 million in the past five years.
• More than 11,000 patents have been filed / granted related to DNA synthesis technologies since 2016, establishing a strong portfolio of intellectual property within this industry.
• The DNA synthesis services market is expected to witness an annualized growth rate of more than 21.5% till 2035; the opportunity is likely to be distributed across method of synthesis, application area, company size and geography.

DNA SYNTHESIS TECHNOLOGIES AND SERVICES MARKET: KEY SEGMENTS

Chemical Method Segment Occupies the Largest Share of the DNA Synthesis Technologies and Services Market

Based on the method of DNA synthesis, the market is segmented into chemical method and enzymatic method. At present, the chemical method of DNA synthesis holds the maximum share of the global DNA synthesis technologies and services market. Additionally, the enzymatic method segment is likely to grow at a faster pace owing to the increasing use of enzymes for DNA isolation and synthesis.

By Key Application Area, Therapeutics is the Fastest Growing Segment of the Global DNA Synthesis Technologies and Services Market

Based on the key application area, the market is segmented into research and diagnostics, and therapeutics. Currently, the research and diagnostics segment captures the highest proportion of the global DNA synthesis technologies and services market. It is worth highlighting that the DNA synthesis technologies and services market for therapeutics segment is likely to grow at a relatively higher CAGR.

Large Company Size Segment Occupy the Largest Share of the DNA Synthesis Technologies and Services Market by Company Size

Based on the company size, the market is segmented into small, mid-sized and large companies. At present, the large companies segment holds the maximum share of the DNA synthesis technologies and services market. Further, it is worth highlighting that the DNA synthesis technologies and services market for small companies' segment is likely to grow at a relatively higher CAGR.

North America Accounts for the Largest Share of the Market

Based on key geographical regions, the market is segmented into North America, Europe, Asia-Pacific and Rest of the World. Currently, North America dominates the global DNA synthesis technologies and services market and accounts for the largest revenue share.

Example Players in the DNA Synthesis Technologies and Services Market

• Ajinomoto Bio-Pharma Services
• ATUM
• DNA Script
• Eurofins Genomics
• Gene Universal
• GenScript
• Synbio Technologies

DNA SYNTHESIS TECHNOLOGIES AND SERVICES MARKET: RESEARCH COVERAGE

• Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the global DNA synthesis technologies and services market, focusing on key market segments, including [A] method of DNA synthesis, [B] key application area, [C] company size and [D] key geographical regions.
• Market Landscape: A comprehensive evaluation of DNA synthesis technologies and services, based on several relevant parameters, such as [A] type of offering, [B] method of DNA synthesis, [C] type of DNA molecule, [D] custom offerings and [E] application area. Additionally, the report provides information on drug developers, focusing on [F] year of establishment, [G] company size and [H] location of headquarters.
• Company Profiles: In-depth profiles of key players engaged in providing technologies and services for DNA synthesis, focusing on [A] overview of the company, [B] financial information (if available), [C] technology / service portfolio, and [D] recent developments and [E] an informed future outlook.
• Case Study 1: A detailed discussion on the current market landscape of oligonucleotide manufacturers focused on research and diagnostic applications, based on [A] year of establishment, [B] company size, [C] scale of operation, [D] location of headquarters, [E] number of manufacturing facilities, [F] location of facility, [G] regulatory accreditations and certifications received, [H] type of oligonucleotide manufactured, [I] type of offering, [J] type of manufacturing service(s) offered and [K] type of modification(s) offered.
• Case Study 2: A detailed discussion on the current market landscape of oligonucleotide manufacturers focused on research and therapeutic applications, based on [A] year of establishment, [B] company size, [C] scale of operation, [D] location of headquarters, [E] number of manufacturing facilities, [F] location of facility, [G] regulatory accreditations and certifications received, [H] type of oligonucleotide manufactured, [I] type of offering, [J] type of manufacturing service(s) offered and [K] type of modification(s) offered.
• Partnerships and Collaborations: An insightful analysis of the deals inked by stakeholders in the DNA synthesis technologies and services market, based on several parameters, such as [A] year of partnership, [B] type of partnership, [C] type of partner, [D] most active players (in terms of the number of partnerships signed) and [E] geographical distribution of partnership activity.
• Funding and Investment Analysis: An in-depth analysis of the fundings raised by DNA synthesis technologies and services companies, based on relevant parameters, such as [A] year of funding, [B] amount invested, [C] type of funding, [D] leading players, [E] leading investors and [F] geography.
• Grants Analysis: An in-depth analysis of academic grants that have been awarded to various research institutes for projects related to DNA synthesis technologies and services, based on relevant parameters, such as [A] year of grant award, [B] amount awarded, [C] type of funding institute, [D] popular NIH departments, [E] support period, [F] emerging focus area, [G] purpose of grants, [H] grant activity code, [I] local recipients, [J] type of recipient organization, [K] study section and [L] type of grant application. The chapter also highlights the popular recipient organizations and prominent program officers.
• Publication Analysis: An insightful analysis of more than 12,000 peer-reviewed scientific articles related to research on DNA synthesis technologies, based on various relevant parameters, such as [A] year of publication, [B] key focus area, [C] type of article, [D] popular keywords, [E] popular authors, [F] therapeutic area, [G] geography and [H] key journals.
• Patent Analysis: An in-depth analysis of patents filed / granted till date in the autoinjectors domain, based on various relevant parameters, such as [A] publication year, [B] geography, [C] CPC symbols, [D] emerging focus areas, [E] type of applicant, [F] leading industry players and [G] patent valuation.

KEY QUESTIONS ANSWERED IN THIS REPORT

• How many companies are currently engaged in this market?
• Which are the leading companies in this market?
• What factors are likely to influence the evolution of this market?
• What is the current and future market size?
• What is the CAGR of this market?
• How is the current and future market opportunity likely to be distributed across key market segments?

REASONS TO BUY THIS REPORT

• The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
• Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
• The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.

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TABLE OF CONTENTS

1. PREFACE

• 1.1. Scope of the Report
• 1.2. Research Methodology
• 1.3. Key Questions Answered
• 1.4. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION

• 3.1. Chapter Overview
• 3.2. Introduction to DNA Synthesis
• 3.3. Components of DNA Synthesis
  • 3.3.1. Substrates
  • 3.3.2. Template
  • 3.3.3. Primer
  • 3.3.4. Enzymes
  • 3.3.5. Leading Strand Synthesis
  • 3.3.6. Lagging Strand Synthesis
• 3.4. DNA Synthesis Technologies
  • 3.4.1. Chemical Method of DNA Synthesis
  • 3.4.2. Enzymatic Method of DNA Synthesis
• 3.5. Applications of DNA Synthesis
• 3.6. Future Perspectives

4. MARKET OVERVIEW: DNA SYNTHESIS TECHNOLOGIES AND SERVICES

• 4.1. Chapter Overview
• 4.2. DNA Synthesis Technologies and Services: Overall Market Landscape
  • 4.2.1. Analysis by Type of Offering
  • 4.2.2. Analysis by Method of DNA Synthesis
  • 4.2.3. Analysis by Type of DNA Molecule
  • 4.2.4. Analysis by Custom Offerings
  • 4.2.5. Analysis by Application Area
• 4.3. DNA Synthesis Technologies and Services: Key Industry Players
  • 4.3.1. Analysis by Year of Establishment
  • 4.3.2. Analysis by Company Size
  • 4.3.3. Analysis by Location of Headquarters
  • 4.3.4. Analysis by Application Area and Region

5. COMPANY PROFILES

• 5.1. Chapter Overview
• 5.2. Ajinomoto Bio-Pharma Services
  • 5.2.1. Company Overview
  • 5.2.2. Financial Information
  • 5.2.3. Technology / Service Portfolio
  • 5.2.4. Recent Developments and Future Outlook
• 5.3. ATUM
  • 5.3.1. Company overview
  • 5.3.2. Technology / Service Portfolio
  • 5.3.3. Recent Developments and Future Outlook
• 5.4. DNA Script
  • 5.4.1. Company Overview
  • 5.4.2. Technology / Service Portfolio
  • 5.4.3. Recent Developments and Future Outlook
• 5.5. Eurofins Genomics
  • 5.5.1. Company Overview
  • 5.5.2. Financial Information
  • 5.5.3. Technology / Service Portfolio
  • 5.5.4. Recent Developments and Future Outlook
• 5.6. Gene Universal
  • 5.6.1. Company Overview
  • 5.6.2. Technology / Service Portfolio
  • 5.6.3. Recent Developments and Future Outlook
• 5.7. GenScript
  • 5.7.1. Company Overview
  • 5.7.2. Financial Information
  • 5.7.3. Technology / Service Portfolio
  • 5.7.4. Recent Developments and Future Outlook
• 5.8. Synbio Technologies
  • 5.8.1. Company overview
  • 5.8.2. Technology / Service Portfolio
  • 5.8.3. Recent Developments and Future Outlook

6. CASE STUDY: OLIGONUCLEOTIDE MANUFACTURERES (RESEARCH AND DIAGNOSTIC APPLICATIONS)

• 6.1. Chapter Overview
• 6.2. Oligonucleotide Manufacturers Focused on Research and Diagnostic Applications: Overall Market Landscape
  • 6.2.1. Analysis by Year of Establishment
  • 6.2.2. Analysis by Company Size
  • 6.2.3. Analysis by Scale of Operation
  • 6.2.4. Analysis by Geographical Location
  • 6.2.5. Analysis by Location of Manufacturing Facilities
  • 6.2.6. Analysis by Regulatory Accreditations / Certifications Received
  • 6.2.7. Analysis by Type of Oligonucleotide Manufactured
  • 6.2.8. Analysis by Type of Offering
  • 6.2.9. Analysis by Type of Manufacturing Service Offered
  • 6.2.10. Analysis by Type of Modification

7. CASE STUDY: OLIGONUCLEOTIDE MANUFACTURERES (THERAPEUTIC APPLICATIONS)

• 7.1. Chapter Overview
• 7.2. Oligonucleotide Manufacturers Focused on Therapeutic Applications: Overall Market Landscape
  • 7.2.1. Analysis by Year of Establishment
  • 7.2.2. Analysis by Company Size
  • 7.2.3. Analysis by Scale of Operation
  • 7.2.4. Analysis by Geographical Location
  • 7.2.5. Analysis by Location of Manufacturing Facilities
  • 7.2.6. Analysis by Regulatory Accreditations / Certifications
  • 7.2.7. Analysis by Type of Oligonucleotide Manufactured
  • 7.2.8. Analysis by Type of Offering
  • 7.2.9. Analysis by Type of Manufacturing Service Offered
  • 7.2.10. Analysis by Type of Modification

8. PARTNERSHIPS AND COLLABORATIONS

• 8.1. Chapter Overview
• 8.2. Partnership Models
• 8.3. DNA Synthesis Technologies and Services: List of Partnerships and Collaborations
  • 8.3.1. Analysis by Year of Partnership
  • 8.3.2. Analysis by Type of Partnership
  • 8.3.3. Analysis by Type of Partner
  • 8.3.4. Analysis by Year and Type of Partner
  • 8.3.5. Most Active Players: Analysis by Number of Partnerships
  • 8.3.6. Regional Analysis
    • 8.3.6.1. Intercontinental and Intracontinental Agreements

9. FUNDING AND INVESTMENT ANALYSIS

• 9.1. Chapter Overview
• 9.2. Types of Funding
• 9.3. DNA Synthesis Technologies: Recent Funding Instances
• 9.4. Analysis by Year of Investment
• 9.5. Analysis by Amount Invested
• 9.6. Analysis by Amount Invested
• 9.7. Analysis by Type of Funding and Amount Invested
• 9.8. Analysis by Venture Capital Funding
• 9.9. Most Active Players: Analysis by Number of Funding Instances
• 9.10. Key Investors: Analysis by Number of Funding Instances
• 9.11. Regional Analysis by Amount Invested
• 9.12. Funding and Investment Summary

10. GRANT ANALYSIS

• 10.1. Chapter Overview
• 10.2. Analysis Methodology and Key Parameters
• 10.3. DNA Synthesis Technologies and Services: List of Academic Grants
  • 10.3.1. Analysis by Year of Grant Award
  • 10.3.2. Analysis by Grant Amount Awarded
  • 10.3.3. Analysis by Administering Institute Center
  • 10.3.4. Analysis by Support Period
  • 10.3.5. Analysis by Administering Institute Center and Support Period
  • 10.3.6. Analysis by Type of Grant Application
  • 10.3.7. Analysis by Grant Activity Code
  • 10.3.8. Word Cloud of Study Titles
  • 10.3.9. Analysis by Purpose of Grant Award
  • 10.3.10. Popular NIH Departments: Analysis by Number of Grants
  • 10.3.11. Analysis by Type of Recipient Organization

10..12. Prominent Program Officers: Analysis by Number of Grants

11. PUBLICATION ANALYSIS

• 11.1. Chapter Overview
• 11.2. Analysis Methodology and Key Parameters
• 11.3. Analysis by Year of Publication
• 11.4. Analysis by Quarterly Distribution of Publication
• 11.5. Analysis by Type of Article
• 11.6. Analysis by Popular Keywords
• 11.7. Most Popular Authors: Analysis by Number of Publications
• 11.8. Popular Publishers: Analysis by Number of Publications
• 11.9. Popular Journals: Analysis by Number of Publications
• 11.10. Analysis by Therapeutic Area
• 11.11. Geographical Analysis

12. PATENT ANALYSIS

• 12.1. Chapter Overview
• 12.2. Analysis Methodology and Key Parameters
• 12.3. DNA Synthesis Technologies and Services: Patent Analysis
  • 12.3.1. Analysis by Type of Patent
  • 12.3.2. Analysis by Publication Year
  • 12.3.3. Analysis by Type of Patent and Publication Year
  • 12.3.4. Analysis by Issuing Authority
  • 12.3.5. Analysis by CPC Symbols
  • 12.3.6. Analysis by Type of Applicant
  • 12.3.7. Word Cloud Analysis: Emerging Focus Areas
  • 12.3.8. Leading Industry Players: Analysis by Number of Patents
  • 12.3.9. Leading Non-Industry Players: Analysis by Number of Patents
  • 12.3.10. Leading Players: Analysis by Number of Patents
  • 12.3.11. Leading Patents: International Patents
  • 12.3.12. Analysis by Patent Characteristics
  • 12.3.13. Patent Valuation Analysis

13. DNA SYNTHESIS SERVICES: MARKET FORECAST AND OPPORTUNITY ANALYSIS

• 13.1. Chapter Overview
• 13.2. Key Assumptions and Forecast Methodology
• 13.3. Global DNA Synthesis Services Market, Till 2035
  • 13.3.1. Global DNA Synthesis Services Market: Distribution by Method of DNA Synthesis, Till 2035
  • 13.3.2. Global DNA Synthesis Services Market: Distribution by Application Area, Till 2035
  • 13.3.3. Global DNA Synthesis Services Market: Distribution by Company Size, Till 2035
  • 13.3.4. Global DNA Synthesis Services Market: Distribution by Geography, Till 2035
• 13.4. DNA Synthesis Services Market in North America, Till 2035
  • 13.4.1. DNA Synthesis Services Market in North America: Distribution by Method of DNA Synthesis, Till 2035
  • 13.4.2. DNA Synthesis Services Market in North America: Distribution by Application Area, Till 2035
  • 13.4.3. DNA Synthesis Services Market in North America: Distribution by Company Size, Till 2035
• 13.5. DNA Synthesis Services Market in Europe, Till 2035
  • 13.5.1. DNA Synthesis Services Market in Europe: Distribution by Method of DNA Synthesis, Till 2035
  • 13.5.2. DNA Synthesis Services Market in Europe: Distribution by Application Area, Till 2035
  • 13.5.3. DNA Synthesis Services Market in Europe: Distribution by Company Size, Till 2035
• 13.6. DNA Synthesis Services Market in Asia-Pacific and Rest of the World, Till 2035
  • 13.6.1. DNA Synthesis Services Market in Asia-Pacific and Rest of the World: Distribution by Method of DNA Synthesis, Till 2035
  • 13.6.2. DNA Synthesis Services Market in Asia-Pacific and Rest of the World: Distribution by Application Area, Till 2035
  • 13.6.3. DNA Synthesis Services Market in Asia-Pacific and Rest of the World: Distribution by Company Size, Till 2035

14. CONCLUDING REMARKS

15. APPENDIX 1: TABULATED DATA

16. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS